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Order NO. D125243
兔抗RNF111多克隆抗體
英文名 Anti-RNF111 rabbit polyclonal antibody
別名 ring finger protein 111; ARK; hRNF111
相關類別 一抗 儲存 冷凍(-20℃)
宿主 Rabbit 反應種屬 Human, Mouse
標記物 Unconjugate 克隆類型 rabbit polyclonal
抗原 RNF111
編 號 包裝 庫存 目錄價(¥) 您的價格(¥) 數 量
D125243-0025 25 ul 現貨
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D125243-0100 100 ul 現貨
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D125243-0200 200 ul 現貨
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技術規格

Background: The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Applications: ELISA, WB, IHC
Name of antibody: RNF111
Immunogen: Fusion protein of human RNF111
Full name: ring finger protein 111
Synonyms: ARK; hRNF111
SwissProt: Q6ZNA4
ELISA Recommended dilution: 5000-10000
IHC positive control: Human gastric cancer
IHC Recommend dilution: 50-300
WB Predicted band size: 109 kDa
WB Positive control: TM4 cell lysate
WB Recommended dilution: 200-1000
相關文檔
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using D125243(RNF111 Antibody) at dilution 1/50. (Original magnification: ×200)

  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: TM4 cell lysate, Primary antibody: D125243(RNF111 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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