Order NO. D126174
兔抗CCDC134多克隆抗體
| 英文名 | Anti-CCDC134 rabbit polyclonal antibody | ||
| 別名 | coiled-coil domain containing 134 | ||
| 相關類別 | 一抗 | 儲存 | 冷凍（-20℃） |
| 宿主 | Rabbit | 反應種屬 | Human, Mouse, Rat |
| 標記物 | Unconjugate | 克隆類型 | rabbit polyclonal |
| 抗原 | CCDC134 | ||
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| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D126174-0025 | 25 ul | 現貨 |  |
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| D126174-0100 | 100 ul | 現貨 | |
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| D126174-0200 | 200 ul | 現貨 | |
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技術規格
| Background: | In extracellular secreted form, promotes proliferation and activation of CD8+ T cells, suggesting a cytokine-like function (PubMed:25125657). Enhances cytotoxic anti-tumor activity of CD8+ T cells (PubMed:25125657). May inhibit ERK and JNK signaling activity (PubMed:18087676, PubMed:23070808). May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling (PubMed:23070808). In the nucleus, enhances stability of the PCAF histone acetyltransferase (HAT) complex member TADA2A and thus promotes PCAF-mediated H3K14 and H4K8 HAT activity. May inhibit TADA2A-mediated TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote TADA2A-mediated XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage. |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | CCDC134 |
| Immunogen: | Fusion protein of human CCDC134 |
| Full name: | coiled-coil domain containing 134 |
| SwissProt: | Q9H6E4 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human tonsil and Human thyroid cancer |
| IHC Recommend dilution: | 50-200 |
| WB Predicted band size: | 27 kDa |
| WB Positive control: | 293T, HepG2 cell, Human fetal liver tissue, Human liver tissue, TM4 cell lysates |
| WB Recommended dilution: | 1000-5000 |
相關文檔
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Sample Application
