概述

Fusion protein corresponding to a region derived from 22-580 amino acids of Human CD93

技術規格

Full name:	CD93 molecule
Synonyms:	C1QR1; C1qRP; CDw93; ECSM3; MXRA4; C1qR(P); dJ737E23.1
Swissprot:	Q9NPY3
Purity:	>95%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	HEK293
Tags:	mFc tag C-Terminus
Species:	Human
Molecular mass:	The protein has a predicted molecular weight of 84.5 kDa after removal of the signal peptide. The apparent molecular weight of CD93-mFc is approximately 100-130 kDa due to glycosylation.
Research areas:	Cardiovascular, Immunology, Stem Cells
Background:	The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.