Order NO. D151204
兔抗PTEN(Phospho-Ser370) 多克隆抗體
| 英文名 | Anti-PTEN(Phospho-Ser370) rabbit polyclonal antibody | ||
| 別名 | This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded t | ||
| 相關類別 | 一抗 | 儲存 | 冷凍（-20℃） 避光 |
| 宿主 | Rabbit | 反應種屬 | Human Mouse Rat |
| 標記物 | Unconjugate | 克隆類型 | rabbit polyclonal |
| 抗原 | PTEN(Phospho-Ser370) | ||
|
|||
| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D151204-0025 | 25 ul | 預計7日內發貨 |
|
|
|
| D151204-0100 | 100 ul | 預計7日內發貨 |
|
|
|
| D151204-0200 | 200 ul | 預計7日內發貨 |
|
|
|
技術規格
| Background: | This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. |
| Applications: | WB, IHC, IF |
| Name of antibody: | PTEN(Phospho-Ser370) |
| Immunogen: | Peptide sequence around phosphorylation site of serine 370(D-V-S(p)-D-N) derived from Human PTEN. |
| Full name: | phosphatase and tensin homolog |
| Synonyms： | 0 |
| SwissProt: | P60484 |
| IHC positive control: | Human breast carcinoma tissue |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 47 kDa |
| WB Positive control: | Hela cells lysate |
| WB Recommended dilution: | 500-1000 |
| IF positive control: | MCF7 cells |
| IF Recommend dilution: | 100-200 |
相關文檔
|
||||
Sample Application
