This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors.
Applications:
IHC
Name of antibody:
BLK(Phospho-Tyr501)
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK.
Full name:
BLK proto-oncogene, Src family tyrosine kinase
Synonyms:
MODY11
SwissProt:
P51451
IHC positive control:
Human breast carcinoma tissue
IHC Recommend dilution:
50-100
相關文檔
Sample Application
The image on the left is immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using D151291(BLK(Phospho-Tyr501) Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)