The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.
Applications:
WB
Name of antibody:
AXL(Phospho-Tyr702)
Immunogen:
Synthetic peptide of human AXL
Full name:
AXL receptor tyrosine kinase
Synonyms:
ARK; UFO; JTK11; Tyro7
SwissProt:
P30530
WB Predicted band size:
98 kDa
WB Positive control:
293 whole cell lysates
WB Recommended dilution:
500-1000
相關文檔
Sample Application
Gel: 6%SDS-PAGE, Lysate: 30 μg, Lane: 293 whole cell lysates, Primary antibody: D155318(AXL(Phospho-Tyr702) Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute