Order NO. D162004
兔抗TP53INP1多克隆抗體
| 英文名 | Anti-TP53INP1 rabbit polyclonal antibody | ||
| 別名 | SIP; Teap; p53DINP1; TP53DINP1; TP53INP1A; TP53INP1B | ||
| 相關類別 | 一抗 | 儲存 | 冷凍（-20℃） |
| 宿主 | Rabbit | 反應種屬 | Human |
| 標記物 | Unconjugate | 克隆類型 | rabbit polyclonal |
| 抗原 | TP53INP1 | ||
|
|||
| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D162004-0025 | 25 ul | 現貨 |  |
|
|
| D162004-0100 | 100 ul | 現貨 | |
|
|
| D162004-0200 | 200 ul | 現貨 | |
|
|
技術規格
| Background: | TP53INP1 (tumor protein p53-inducible nuclear protein 1), also known as p53DINP1, SIP or Teap, is a 240 amino acid protein that localizes to nuclear bodies and exists as two alternatively spliced isoforms, designated p53DINP1a and p53DINP1b. Expressed ubiquitously with higher expression in testis, pancreas and spleen tissue, TP53INP1 functions in response to double-stranded DNA breaks and regulates p53-mediated apoptosis, specifically by phosphorylating human p53 at Ser 46, an event that leads to cell death. Additionally, TP53INP1 is thought to interact with p73 and may be involved in the regulation of p73-controlled cell cycle progression. TP53INP1 expression is downregulated in pancreatic ductal adenocarcinomas, suggesting that, via its ability to induce cell death, TP53INP1 plays a role in tumor suppression. |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | TP53INP1 |
| Immunogen: | Synthetic peptide of human TP53INP1 |
| Full name: | tumor protein p53 inducible nuclear protein 1 |
| Synonyms： | SIP; Teap; p53DINP1; TP53DINP1; TP53INP1A; TP53INP1B |
| SwissProt: | Q96A56 |
| ELISA Recommended dilution: | 1000-2000 |
| IHC positive control: | Human brain and Human prostate cancer |
| IHC Recommend dilution: | 50-200 |
| WB Predicted band size: | 27 kDa |
| WB Positive control: | Human fetal liver tissue, 293T and 231 cells |
| WB Recommended dilution: | 200-1000 |
相關文檔
 |
||||
Sample Application
