Order NO. D190667
小鼠抗RAD51單克隆抗體
英文名 | Anti-RAD51 mouse monoclonal antibody | ||
別名 | RAD51 recombinase; RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930 | ||
相關類別 | 一抗 | 儲存 | 冷凍(-20℃) |
宿主 | Mouse | 反應種屬 | Human, Mouse, Rat, Monkey |
標記物 | Unconjugate | 克隆類型 | Mouse Monoclonal |
抗原 | RAD51 | ||
編 號 | 包裝 | 庫存 | 目錄價(¥) | 您的價格(¥) | 數 量 |
D190667-0100 | 100 ul | 預計5日內發貨 |
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技術規格
Background: | The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Applications: | WB |
Name of antibody: | RAD51 |
Immunogen: | Fusion protein of human RAD51 |
Full name: | RAD51 recombinase |
Synonyms: | RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930 |
SwissProt: | Q06609 |
WB Predicted band size: | 37 kDa |
WB Positive control: | CHO-K1, COS7, C6, 3T3 and Hela cell lysates |
WB Recommended dilution: | 1000-5000 |