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Order NO. D194557
小鼠抗CD46單克隆抗體
英文名 Anti-CD46 mouse monoclonal antibody
別名 CD46 molecule; MCP; TLX; AHUS2; MIC10; TRA2.10
相關類別 一抗 儲存 冷凍(-20℃)
宿主 Mouse 反應種屬 Human
標記物 Unconjugate 克隆類型 mouse monoclonal
抗原 CD46
編 號 包裝 庫存 目錄價(¥) 您的價格(¥) 數 量
D194557-0100 100 ul 預計5日內發貨
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技術規格

Background: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Applications: WB, IF, FC
Name of antibody: CD46
Immunogen: Fusion protein of human CD46
Full name: CD46 molecule
Synonyms: MCP; TLX; AHUS2; MIC10; TRA2.10
SwissProt: P15529
WB Predicted band size: 44 kDa
WB Positive control: SW480 cell lysate
WB Recommended dilution: 500-2000
IF Positive control: Hela cells
IF Recommended dilution: 200-1000
FC Recommended dilution: 200-400
相關文檔
Sample Application

  • The image is flow cytometry analysis of HL-60 cells using D194557(CD46 antibody) at dilution 1/400 (green) and negative control (red).

  • The image is immunofluorescence of Hela cells using D194557(CD46 Antibody) at dilution 1/200 (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

  • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane: SW480 cell lysate, Primary antibody: D194557(CD46 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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