Order NO. D194557
小鼠抗CD46單克隆抗體
英文名 | Anti-CD46 mouse monoclonal antibody | ||
別名 | CD46 molecule; MCP; TLX; AHUS2; MIC10; TRA2.10 | ||
相關類別 | 一抗 | 儲存 | 冷凍(-20℃) |
宿主 | Mouse | 反應種屬 | Human |
標記物 | Unconjugate | 克隆類型 | mouse monoclonal |
抗原 | CD46 | ||
編 號 | 包裝 | 庫存 | 目錄價(¥) | 您的價格(¥) | 數 量 |
D194557-0100 | 100 ul | 預計5日內發貨 |
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技術規格
Background: | The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010] |
Applications: | WB, IF, FC |
Name of antibody: | CD46 |
Immunogen: | Fusion protein of human CD46 |
Full name: | CD46 molecule |
Synonyms: | MCP; TLX; AHUS2; MIC10; TRA2.10 |
SwissProt: | P15529 |
WB Predicted band size: | 44 kDa |
WB Positive control: | SW480 cell lysate |
WB Recommended dilution: | 500-2000 |
IF Positive control: | Hela cells |
IF Recommended dilution: | 200-1000 |
FC Recommended dilution: | 200-400 |