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Order NO. D194746
小鼠抗TP63單克隆抗體
英文名 Anti-TP63 mouse monoclonal antibody
別名 tumor protein p63; AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4; TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p5
相關類別 一抗 儲存 冷凍(-20℃)
宿主 Mouse 反應種屬 Human, Mouse, Rat, Monkey
標記物 Unconjugate 克隆類型 mouse monoclonal
抗原 TP63
編 號 包裝 庫存 目錄價(¥) 您的價格(¥) 數 量
D194746-0100 100 ul 預計5日內發貨
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技術規格

Background: This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016]
Applications: WB, IHC
Name of antibody: TP63
Immunogen: Synthetic peptide of human TP63
Full name: tumor protein p63
Synonyms: AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4; TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p51B)
SwissProt: Q9H3D4
IHC positive control: Human ovarian cancer and Human lung cancer
IHC Recommend dilution: 200-1000
WB Predicted band size: 77 kDa
WB Positive control: A431, Hela, Jurkat, THP-1, NIH/3T3, COS-7 and PC-12 cell lysates
WB Recommended dilution: 500-2000
相關文檔
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using D194746(TP63 Antibody) at dilution 1/800. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using D194746(TP63 Antibody) at dilution 1/800. (Original magnification: ×200)

  • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane 1-7: A431, Hela, Jurkat, THP-1, NIH/3T3, COS-7 and PC-12 cell lysates , Primary antibody: D194746(TP63 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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