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Order NO. D224432
兔抗CCDC112多克隆抗體
英文名 Anti-CCDC112 rabbit polyclonal antibody
別名 coiled-coil domain containing 112; MBC1
相關類別 一抗 儲存 冷凍(-20℃)
宿主 Rabbit 反應種屬 Human, Mouse
標記物 Unconjugate 克隆類型 rabbit polyclonal
抗原 CCDC112
編 號 包裝 庫存 目錄價(¥) 您的價格(¥) 數 量
D224432-0025 25 ul 現貨
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D224432-0100 100 ul 現貨
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D224432-0200 200 ul 現貨
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技術規格

Background: CCDC112 (coiled-coil domain containing 112), also known as MBC1 (mutated in bladder cancer 1), is a 446 amino acid protein. The gene encoding CCDC112 is located on chromosome 5. Due to alternative splicing events, CCDC112 exists as two isoforms. Chromosome 5 comprises about 6% of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Applications: ELISA, IHC
Name of antibody: CCDC112
Immunogen: Fusion protein of human CCDC112
Full name: coiled-coil domain containing 112
Synonyms: MBC1
SwissProt: Q8NEF3
ELISA Recommended dilution: 5000-10000
IHC positive control: Human prostate cancer and human esophagus cancer
IHC Recommend dilution: 40-200
相關文檔
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using D224432(CCDC112 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using D224432(CCDC112 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)

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