Order NO. D224518
兔抗CEP57多克隆抗體
| 英文名 | Anti-CEP57 rabbit polyclonal antibody | ||
| 別名 | centrosomal protein 57; MVA2; PIG8; TSP57 | ||
| 相關類別 | 一抗 | 儲存 | 冷凍（-20℃） |
| 宿主 | Rabbit | 反應種屬 | Human, Mouse, Rat |
| 標記物 | Unconjugate | 克隆類型 | rabbit polyclonal |
| 抗原 | CEP57 | ||
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| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D224518-0025 | 25 ul | 現貨 |  |
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| D224518-0100 | 100 ul | 現貨 | |
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| D224518-0200 | 200 ul | 現貨 | |
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技術規格
| Background: | This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | CEP57 |
| Immunogen: | Full length fusion protein |
| Full name: | centrosomal protein 57 |
| Synonyms: | MVA2; PIG8; TSP57 |
| SwissProt: | Q86XR8 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human liver cancer and Human esophagus cancer |
| IHC Recommend dilution: | 25-100 |
| WB Predicted band size: | 57 kDa |
| WB Positive control: | A549 cell lysate |
| WB Recommended dilution: | 500-2000 |
相關文檔
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Sample Application
