Order NO. D225189
兔抗C9orf116多克隆抗體
英文名 | Anti-C9orf116 rabbit polyclonal antibody | ||
別名 | chromosome 9 open reading frame 116; PIERCE1; RbEST47 | ||
相關類別 | 一抗 | 儲存 | 冷凍(-20℃) |
宿主 | Rabbit | 反應種屬 | Human |
標記物 | Unconjugate | 克隆類型 | rabbit polyclonal |
抗原 | C9orf116 | ||
編 號 | 包裝 | 庫存 | 目錄價(¥) | 您的價格(¥) | 數 量 |
D225189-0025 | 25 ul | 現貨 |
|
||
D225189-0100 | 100 ul | 現貨 |
|
||
D225189-0200 | 200 ul | 現貨 |
|
技術規格
Background: | C9orf116, also known as PIERCE1. PIERCE1 is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies. |
Applications: | ELISA, IHC |
Name of antibody: | C9orf116 |
Immunogen: | Fusion protein of human C9orf116 |
Full name: | chromosome 9 open reading frame 116 |
Synonyms: | PIERCE1; RbEST47 |
SwissProt: | Q5BN46 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human thyroid cancer |
IHC Recommend dilution: | 50-300 |