Order NO. D225243
兔抗RNF111多克隆抗體
| 英文名 | Anti-RNF111 rabbit polyclonal antibody | ||
| 別名 | ring finger protein 111; ARK; hRNF111 | ||
| 相關類別 | 一抗 | 儲存 | 冷凍（-20℃） |
| 宿主 | Rabbit | 反應種屬 | Human |
| 標記物 | Unconjugate | 克隆類型 | rabbit polyclonal |
| 抗原 | RNF111 | ||
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| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D225243-0025 | 25 ul | 現貨 |  |
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| D225243-0100 | 100 ul | 現貨 | |
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| D225243-0200 | 200 ul | 現貨 | |
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技術規格
| Background: | The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. |
| Applications: | ELISA, IHC |
| Name of antibody: | RNF111 |
| Immunogen: | Fusion protein of human RNF111 |
| Full name: | ring finger protein 111 |
| Synonyms: | ARK; hRNF111 |
| SwissProt: | Q6ZNA4 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human gastric cancer and Human thyroid cancer |
| IHC Recommend dilution: | 50-300 |
相關文檔
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Sample Application
