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Order NO. D261589
兔抗NLRP3多克隆抗體
英文名 Anti-NLRP3 rabbit polyclonal antibody
別名 AII; AVP; FCU; MWS; FCAS; CIAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL
相關類別 一抗 儲存 冷凍(-20℃)
宿主 Rabbit 反應種屬 Human, Mouse
標記物 Unconjugate 克隆類型 rabbit polyclonal
抗原 NLRP3
編 號 包裝 庫存 目錄價(¥) 您的價格(¥) 數 量
D261589-0025 25 ul 現貨
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D261589-0100 100 ul 現貨
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D261589-0200 200 ul 現貨
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技術規格

Background: This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID).
Applications: ELISA, IHC
Name of antibody: NLRP3
Immunogen: Synthetic peptide of human NLRP3
Full name: NLR family, pyrin domain containing 3
Synonyms: AII; AVP; FCU; MWS; FCAS; CIAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL
SwissProt: Q96P20
IHC positive control: Human gastric cancer and human thyroid cancer
IHC Recommend dilution: 25-100
相關文檔
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using D261589(NLRP3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using D261589(NLRP3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)

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