Order NO. D261589
兔抗NLRP3多克隆抗體
英文名 | Anti-NLRP3 rabbit polyclonal antibody | ||
別名 | AII; AVP; FCU; MWS; FCAS; CIAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL | ||
相關類別 | 一抗 | 儲存 | 冷凍(-20℃) |
宿主 | Rabbit | 反應種屬 | Human, Mouse |
標記物 | Unconjugate | 克隆類型 | rabbit polyclonal |
抗原 | NLRP3 | ||
編 號 | 包裝 | 庫存 | 目錄價(¥) | 您的價格(¥) | 數 量 |
D261589-0025 | 25 ul | 現貨 |
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D261589-0100 | 100 ul | 現貨 |
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D261589-0200 | 200 ul | 現貨 |
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技術規格
Background: | This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). |
Applications: | ELISA, IHC |
Name of antibody: | NLRP3 |
Immunogen: | Synthetic peptide of human NLRP3 |
Full name: | NLR family, pyrin domain containing 3 |
Synonyms: | AII; AVP; FCU; MWS; FCAS; CIAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL |
SwissProt: | Q96P20 |
IHC positive control: | Human gastric cancer and human thyroid cancer |
IHC Recommend dilution: | 25-100 |