Order NO. D263255
兔抗CEP131多克隆抗體
| 英文名 | Anti-CEP131 rabbit polyclonal antibody | ||
| 別名 | centrosomal protein 131; AZ1; ZA1; AZI1 | ||
| 相關類別 | 一抗 | 儲存 | 冷凍（-20℃） |
| 宿主 | Rabbit | 反應種屬 | Human |
| 標記物 | Unconjugate | 克隆類型 | rabbit polyclonal |
| 抗原 | CEP131 | ||
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| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D263255-0025 | 25 ul | 現貨 |  |
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| D263255-0100 | 100 ul | 現貨 | |
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| D263255-0200 | 200 ul | 現貨 | |
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技術規格
| Background: | Component of centriolar satellites contributing to the building of a complex and dynamic network required to regulate cilia/flagellum formation (PubMed:17954613, PubMed:24185901). In proliferating cells, MIB1-mediated ubiquitination induces its sequestration within centriolar satellites, precluding untimely cilia formation initiation (PubMed:24121310). In contrast, during normal and ultraviolet or heat shock cellular stress-induced ciliogenesis, its non-ubiquitinated form is rapidly displaced from centriolar satellites and recruited to centrosome/basal bodies in a microtubule- and p38 MAPK-dependent manner (PubMed:24121310, PubMed:26616734). Acts also as a negative regulator of BBSome ciliary trafficking (PubMed:24550735). Plays a role in sperm flagellar formation; may be involved in the regulation of intraflagellar transport (IFT) and/or intramanchette (IMT) trafficking, which are important for axoneme extension and/or cargo delivery to the nascent sperm tail (By similarity). Required for optimal cell proliferation and cell cycle progression; may play a role in the regulation of genome stability in non-ciliogenic cells (PubMed:22797915, PubMed:26297806). Involved in centriole duplication (By similarity). Required for CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (PubMed:26297806). |
| Applications: | ELISA, IHC |
| Name of antibody: | CEP131 |
| Immunogen: | Synthetic peptide of human CEP131 |
| Full name: | centrosomal protein 131 |
| Synonyms: | AZ1; ZA1; AZI1 |
| SwissProt: | Q9UPN4 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human prostate cancer |
| IHC Recommend dilution: | 25-50 |
相關文檔
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Sample Application
