Order NO. D620240
KRT81抗原(重組蛋白)
英文名 | KRT81 Antigen (Recombinant Protein) | ||
相關類別 | 抗原 | 儲存 | 冷凍(-20℃) |
編 號 | 包裝 | 庫存 | 目錄價(¥) | 您的價格(¥) | 數 量 |
D620240-0001 | 1 MG | 預計30日內發貨 |
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D620240-0100 | 100 UG | 預計30日內發貨 |
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產品描述
概述
Fusion protein corresponding to a region derived from 1-300 amino acids of human KRT81
技術規格
Full name: | keratin 81 |
Synonyms: | HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1 |
Swissprot: | Q14533 |
Gene Accession: | BC117465 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Background: | The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. |