Order NO. D620943
FBXO32抗原（重組蛋白）
| 英文名 | FBXO32 Antigen (Recombinant Protein) | ||
| 別名 | Fbx32; MAFbx | ||
| 相關類別 | 抗原 | 儲存 | 冷凍（-20℃） |
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| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D620943-0001 | 1 MG | 預計30日內發貨 |  |
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| D620943-0100 | 100 UG | 預計30日內發貨 | |
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產品描述
概述
Fusion protein corresponding to a region derived from 146-355 amino acids of human FBXO32
技術規格
| Full name: | F-box protein 32 |
| Synonyms: | Fbx32; MAFbx |
| Swissprot: | Q969P5 |
| Gene Accession: | BC024030 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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