Order NO. D622904
TMEM123抗原（重組蛋白）
| 英文名 | TMEM123 Antigen (Recombinant Protein) | ||
| 別名 | KCT3; PORMIN; PORIMIN | ||
| 相關類別 | 抗原 | 儲存 | 冷凍（-20℃） |
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| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D622904-0001 | 1 MG | 預計30日內發貨 |  |
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| D622904-0100 | 100 UG | 預計30日內發貨 | |
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產品描述
概述
Fusion protein corresponding to a region derived from 27-166 amino acids of human TMEM123
技術規格
| Full name: | transmembrane protein 123 |
| Synonyms: | KCT3; PORMIN; PORIMIN |
| Swissprot: | Q8N131 |
| Gene Accession: | BC032296 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. |
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