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Order NO. D623045
RNF128抗原(重組蛋白)
英文名 RNF128 Antigen (Recombinant Protein)
別名 GRAIL
相關類別 抗原 儲存 冷凍(-20℃)
編 號 包裝 庫存 目錄價(¥) 您的價格(¥) 數 量
D623045-0001 1 MG 預計30日內發貨
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D623045-0100 100 UG 預計30日內發貨
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產品描述

概述

Fusion protein corresponding to a region derived from 39-207 amino acids of human RNF128

技術規格

Full name: ring finger protein 128
Synonyms: GRAIL
Swissprot: Q8TEB7
Gene Accession: BC063404
Purity: >85%, as determined by Coomassie blue stained SDS-PAGE
Expression system: Escherichia coli
Tags: His tag C-Terminus, GST tag N-Terminus
Background: The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
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