Order NO. D623045
RNF128抗原(重組蛋白)
英文名 | RNF128 Antigen (Recombinant Protein) | ||
別名 | GRAIL | ||
相關類別 | 抗原 | 儲存 | 冷凍(-20℃) |
編 號 | 包裝 | 庫存 | 目錄價(¥) | 您的價格(¥) | 數 量 |
D623045-0001 | 1 MG | 預計30日內發貨 |
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D623045-0100 | 100 UG | 預計30日內發貨 |
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產品描述
概述
Fusion protein corresponding to a region derived from 39-207 amino acids of human RNF128
技術規格
Full name: | ring finger protein 128 |
Synonyms: | GRAIL |
Swissprot: | Q8TEB7 |
Gene Accession: | BC063404 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Background: | The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |