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Order NO. D623228
RO60抗原(重組蛋白)
英文名 RO60 Antigen (Recombinant Protein)
別名 Ro60, Y RNA binding protein; SSA2; RORNP; TROVE2
相關類別 抗原 儲存 冷凍(-20℃)
編 號 包裝 庫存 目錄價(¥) 您的價格(¥) 數 量
D623228-0001 1 MG 預計30日內發貨
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D623228-0100 100 UG 預計30日內發貨
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產品描述

概述

Fusion protein corresponding to a region derived from 1-538 amino acids of human RO60

技術規格

Full name: Ro60, Y RNA binding protein
Synonyms: SSA2; RORNP; TROVE2
Swissprot: P10155
Gene Accession: BC036658
Purity: >85%, as determined by Coomassie blue stained SDS-PAGE
Expression system: Escherichia coli
Tags: His tag C-Terminus, GST tag N-Terminus
Background: RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation (PubMed:18056422). Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammaotry cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes (PubMed:26382853). May play roles in cilia formation and/or maintenance.
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