Order NO. D623705
ZNF486抗原(重組蛋白)
英文名 | ZNF486 Antigen (Recombinant Protein) | ||
別名 | KRBO2 | ||
相關類別 | 抗原 | 儲存 | 冷凍(-20℃) |
編 號 | 包裝 | 庫存 | 目錄價(¥) | 您的價格(¥) | 數 量 |
D623705-0001 | 1 MG | 預計30日內發貨 |
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D623705-0100 | 100 UG | 預計30日內發貨 |
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產品描述
概述
Fusion protein corresponding to a region derived from 264-463 amino acids of human ZNF486
技術規格
Full name: | zinc finger protein 486 |
Synonyms: | KRBO2 |
Swissprot: | Q96H40 |
Gene Accession: | BC117268 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Background: | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF486 (Zinc finger protein 486), also known as KRAB domain only protein 2, is a 216 amino acid nuclear protein that contains one KRAB domain and two C2H2-type zinc fingers. The gene encoding ZNF486 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. May be involved in transcriptional regulation. |