Order NO. D623984
ZNF281抗原（重組蛋白）
| 英文名 | ZNF281 Antigen (Recombinant Protein) | ||
| 別名 | ZBP-99; ZNP-99 | ||
| 相關類別 | 抗原 | 儲存 | 冷凍（-20℃） |
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| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D623984-0001 | 1 MG | 預計30日內發貨 |  |
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| D623984-0100 | 100 UG | 預計30日內發貨 | |
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產品描述
概述
Fusion protein corresponding to a region derived from 696-895 amino acids of human ZNF281
技術規格
| Full name: | zinc finger protein 281 |
| Synonyms: | ZBP-99; ZNP-99 |
| Swissprot: | Q9Y2X9 |
| Gene Accession: | BC060820 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Krüppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR. |
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