Order NO. D625243
RNF111抗原（重組蛋白）
| 英文名 | RNF111 Antigen (Recombinant Protein) | ||
| 別名 | ARK; hRNF111 | ||
| 相關類別 | 抗原 | 儲存 | 冷凍（-20℃） |
|
|||
| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D625243-0001 | 1 MG | 預計30日內發貨 |  |
|
|
| D625243-0100 | 100 UG | 預計30日內發貨 | |
|
|
產品描述
概述
Fusion protein corresponding to a region derived from 850-986 amino acids of human RNF111
技術規格
| Full name: | ring finger protein 111 |
| Synonyms: | ARK; hRNF111 |
| Swissprot: | Q6ZNA4 |
| Gene Accession: | BC010369 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. |
相關文檔
 |
||||