Order NO. D625873
IFT57抗原（重組蛋白）
| 英文名 | IFT57 Antigen (Recombinant Protein) | ||
| 別名 | HIPPI; MHS4R2; ESRRBL1 | ||
| 相關類別 | 抗原 | 儲存 | 冷凍（-20℃） |
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| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D625873-0001 | 1 MG | 預計30日內發貨 |  |
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| D625873-0100 | 100 UG | 預計30日內發貨 | |
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產品描述
概述
Fusion protein corresponding to a region derived from 230-429 amino acids of human IFT57
技術規格
| Full name: | intraflagellar transport 57 |
| Synonyms: | HIPPI; MHS4R2; ESRRBL1 |
| Swissprot: | Q9NWB7 |
| Gene Accession: | BC011899 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
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