Order NO. D625915
ZAP70抗原（重組蛋白）
| 英文名 | ZAP70 Antigen (Recombinant Protein) | ||
| 別名 | SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70 | ||
| 相關類別 | 抗原 | 儲存 | 冷凍（-20℃） |
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| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D625915-0001 | 1 MG | 預計30日內發貨 |  |
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| D625915-0100 | 100 UG | 預計30日內發貨 | |
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產品描述
概述
Fusion protein corresponding to a region derived from 420-619 amino acids of human ZAP70
技術規格
| Full name: | zeta chain of T cell receptor associated protein kinase 70 |
| Synonyms: | SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70 |
| SwissProt: | P43403 |
| Gene Accession: | BC039039 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. |
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