Order NO. D226036
兔抗CD59多克隆抗體
英文名 | Anti-CD59 rabbit polyclonal antibody | ||
別名 | CD59 molecule (CD59 blood group); 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HR | ||
相關類別 | 一抗 | 儲存 | 冷凍(-20℃) |
宿主 | Rabbit | 反應種屬 | Human |
標記物 | Unconjugate | 克隆類型 | rabbit polyclonal |
抗原 | CD59 | ||
編 號 | 包裝 | 庫存 | 目錄價(¥) | 您的價格(¥) | 數 量 |
D226036-0025 | 25 ul | 現貨 |
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D226036-0100 | 100 ul | 現貨 |
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D226036-0200 | 200 ul | 現貨 |
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技術規格
Background: | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. |
Applications: | ELISA, IHC |
Name of antibody: | CD59 |
Immunogen: | Fusion protein of human CD59 |
Full name: | CD59 molecule (CD59 blood group) |
Synonyms: | 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20 |
SwissProt: | P13987 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human liver cancer |
IHC Recommend dilution: | 200-300 |