概述

Fusion protein corresponding to a region derived from 27-220 amino acids of Human CD48

技術規格

Full name:	CD48 molecule
Synonyms:	BCM1; BLAST; hCD48; mCD48; BLAST1; SLAMF2; MEM-102
Swissprot:	P09326
Purity:	>95%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	HEK293
Tags:	hFc tag C-Terminus
Species:	Human
Molecular mass:	The protein has a predicted molecular weight of 48.5 kDa after removal of the signal peptide. The apparent molecular weight of CD48-hFc is approximately 55-70 kDa due to glycosylation.
Research areas:	Immunology
Background:	This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]