概述

Fusion protein corresponding to a region derived from 22-182 amino acids of Mouse Ifnb1

技術規格

Full name:	interferon beta 1, fibroblast
Synonyms:	Ifb; IFNB; If1da1; IFN-beta
Swissprot:	P01575
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	HEK293
Tags:	6×His tag C-Terminus
Species:	Mouse
Molecular mass:	The protein has a predicted molecular weight of 20.6 kDa after removal of the signal peptide. The apparent molecular weight of Mouse Ifnb1-His is approximately 25-35 kDa due to glycosylation.
Research areas:	Signal Transduction, Cancer, Immunology
Background:	Enables cytokine activity and type I interferon receptor binding activity. Involved in B cell proliferation; cellular response to virus; and type I interferon signaling pathway. Acts upstream of or within several processes, including cellular response to organic cyclic compound; defense response to other organism; and negative regulation of osteoclast differentiation. Located in extracellular space. Is expressed in embryo and liver. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to human IFNB1 (interferon beta 1).